recent advances in gastrointestinal immunology

نویسندگان

luke materacki

david al dulaimi

چکیده

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Recent advances in gastrointestinal immunology.

Biancheri P et al. Abnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease. Gut 2015;0:1-11 The expression of epithelial-derived thymic stromal lymphopoietin (TSLP), a key cytokine modulator of gut immune tolerance, may be dysregulated in coeliac disease (CD). This study investigated TSLP expression along the clinical spectrum of CD and evaluated...

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Recent Advances in Gastrointestinal Stent Development

Endoscopic stenting is increasingly being used in the management of gastrointestinal luminal obstruction, and has become the current treatment of choice for the palliation of blockage caused by malignant or benign growths. A variety of stents have been developed to enhance the efficacy of the procedure, and improvements are ongoing. In this article, we review the history of, and recent advances...

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Recent advances in managing gastrointestinal stromal tumor

Constitutive activating mutations in KIT and platelet-derived growth factor receptor α ( PDGFRα) are heavily involved in the pathobiology of gastrointestinal stromal tumors (GISTs). This disease has served as an effective "proof-of-concept" model for targeting gain-of-function kinase mutations in cancer. This review discusses the current standard of care in terms of pharmacotherapy in the manag...

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Recent Advances in Hemophilia Gene Therapy

Heterogeneous loss of function mutations at F8 and F9 genes causes X-linked recessive bleeding disorders, hemophilia A (HA) and hemophilia B (HB), respectively. HA is clinically indistinguishable from HB and accounts for more than 80% of hemophilia cases; the former affects 1/5000 and the latter 1/25000 male births worldwide. In Iran, it is estimated that around 4300 HA and 900 HB patients are ...

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Editorial: Recent Advances in HBV and HCV Immunology

Viral hepatitis is a major public health problem. While a prophylactic vaccine is now available for hepatitis B virus (HBV), an estimated 240–350 million people worldwide are persistently infected with HBV (1–3). There is not yet an approved vaccine to prevent hepatitis C virus (HCV) infection, and between 130 and 200 million people are believed to be chronically infected worldwide (4–6). Untre...

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Recent Advances in the Immunology and Serological Diagnosis of Echinococcosis

Wenbao Zhang1,2,, Jun Li1,2, Renyong Lin1, Hao Wen1 and Donald P. McManus2 1State Key Laboratory Breeding Base of Xinjiang Major Diseases Research, Clinical Medicine Institute, First Affiliated Hospital of Xinjiang Medical University, Urumqi, 2Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, The Queensland Institute of Medical Research an...

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عنوان ژورنال:
gastroenterology and hepatology from bed to bench

جلد ۱، شماره ۹، صفحات ۲۰۱۶-۹

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